Not for every profession. Some listed professions have a specific degree requirement without an experience substitution, while others allow alternate paths. This depends entirely on the specific profession being considered, so the requirement needs to be checked directly rather than assumed. Do not treat experience as an automatic substitute without confirming it applies to this profession.
Check the specific profession's rules directly
Avoid applying a general assumption that experience always counts toward a degree requirement, since this varies by profession and is not universal. Get the requirement for the exact profession in writing, then compare it against the applicant's actual background. If experience is a recognized substitute for this specific profession, confirm exactly how much and what kind of experience is needed, and gather documentation that clearly demonstrates it.
It helps to know why the answer varies. The listed professions were written individually, and their requirements were not harmonised afterwards, so one profession may accept a post-secondary diploma with several years of experience while its apparent neighbour requires a baccalaureate and nothing else. Reading the entry for the exact profession is therefore not a formality but the whole exercise.
Two further conditions apply regardless of which profession is chosen: the employment must be prearranged with a United States employer or entity, and the applicant must be a citizen of Canada or Mexico. Permanent residence in Canada, however long held, does not satisfy the second.